There is no clear evidence that children with Primary Immunodeficiency (PID) are at great risk of developing COVID-19 or are at greater risk of severe complications from this infection.

Data are still limited regarding the extent of the disease in patients with PID and if patients with PID are chronic shedders of the virus. However, based on expert immunologist opinion (Link), patients with Primary Immune deficiency are  divided into 3 groups based on potential risk for COVID-19. Dr. Reem Elfeky- Immunology consultant at Royal Free Hospital, the UK has created an easy-to-ready flowchart adapted from the UK PIN risk stratification.

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